CanProbe is a joint venture between the University Health Network (UHN) and the Centre for Probe Development and Commercialization (CPDC) to create a Canadian Centre of Excellence for the development, translation, utilization and commercialization of radiopharmaceuticals. CanProbe leverages the strengths of its partners and their affiliates.

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About

CanProbe provides access to specialized expertise that supports the development of new radiopharmaceuticals, with proven experience translating products to the clinical setting, and world-class, GMP, manufacturing capabilities that operate in accordance with FDA, Health Canada and European regulations.

These radiopharmaceuticals are part of an advanced imaging technology that uses medical isotopes to assess and treat patients at a cellular level. Using imaging radiopharmaceuticals, physicians can detect diseases earlier and more accurately monitor the effectiveness of treatments. Targeted therapeutic radiopharmaceuticals can be used to provide personalized treatment of cancers.

Product Pipeline

The safety and efficacy of these investigational products have not been fully established and they have not been approved by Health Canada as commercial products for medicinal use. These products can only be used under an approved clinical trial application (CTA).

Investigational Products

  • [F-18]-DCFPyL
  • [F-18]-FAZA
  • [F-18]-FLT

Press Release

CanProbe joins ARTMS inc and POINT BioPharma in advancing Ga-68 Imaging

Services

Translational & Clinical Research

Development and commercialization of radiopharmaceuticals in support of clinical and research programs.

Process support and analytical chemistry development for preclinical studies or clinical trials.

Regulatory and clinical research support, including for local researchers using our tracers.

Development and validation of process and methods and GMP manufacturing for clinical trial supply.

Technical transfer of existing methods to enable the manufacture of radiopharmaceuticals for clinical trials.

Access to radioisotopes under the Canadian Nuclear Safety Commission (CNSC) licence such as F-18, Ga-68 or Lu-177. Contact us for the complete list.

Radiopharmaceutical Manufacturing

Production of CanProbe products and contract manufacturing on behalf of industry partners.

Distribution of radiopharmaceutical products both locally and abroad.

CanProbe has supported over 40 clinical trials with various investigational products

CanProbe has manufactured over 16,000+ patient doses since 2016

CanProbe has relationships with several pharmaceutical clients to manufacture a variety of radiopharmaceuticals

Team

CanProbe is governed by a Board of Directors with members drawn from the University Health Network UHN) and the Centre for Probe Development and Commercialization (CPDC). Board members oversee the joint venture and ensure the successful operation of CanProbe.

CanProbe Board of Directors:

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Bruno Paquin

President, CanProbe
Business Development, Senior Director, CPDC

LUKE BRZOZOWSKI

Secretary, CanProbe
Senior Director, Techna and Diagnostics Innovation, UHN

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Angela Lauretani

Director, CanProbe
Senior Director, Finance & Administration, CPDC

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Julia Publicover

Director, CanProbe
Program Manager, Techna Institute, UHN

Dr. Ur Metser

Ur Metser

Director, CanProbe
Division Head of Molecular Imaging, UHN

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Anne Goodbody

Director, CanProbe
Chief Regulatory Officer, CPDC

CanProbe Leadership

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David Green

Site Lead, Techna Institute, UHN

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Constantinos Economou

Director, Manufacturing Operations CPDC

Careers

Join Our Team

Senior Process Chemist

Full Time
Toronto, Ontario

The Centre for Probe Development and Commercialization (CPDC) is a global leader in the discovery, development and distribution of next-generation radiopharmaceuticals. Our products are used daily for the detection and treatment of human diseases such as cancer. CPDC offers career growth and development in a highly entrepreneurial environment. CPDC offers medical and dental benefits, sick days and more.

Due to the growing demand for our products, we have an immediate need for Senior Process Chemist to join our CPDC team.

WE OFFER:

  • Competitive compensation including group benefits
  • Opportunity for long-term growth
  • Professional, collaborative environment
  • Innovative and interesting work that makes a positive impact on patients and Canadian healthcare
  • Ability to work day and/or evening shifts

The Senior Process Chemist will work in a fast-paced team setting using state-of-the-art techniques and equipment to develop, manufacture, test and package radiopharmaceutical products.

  • Serve as representative on a project team in the capacity of process chemist expert and project leader
  • Provide project data and progress status updates to management and customers
  • Design and conduct experiments, critically evaluate data, draw appropriate conclusions and develop follow-up plans of action
  • Work with technical / laboratory staff on the development of synthesis, purification, formulation and aseptic filling processes, including process transfer, scale-up, validation and launch activities
  • Prepare and review written procedures, batch records, experimental protocols and reports, specifications, qualification protocols.
  • Conduct work according to best practices and, where appropriate, regulatory guidance, international pharmacopeias, ICH, GMPs, established business processes and protocols, and applicable standard operating procedures
  • Complete all other related duties that support the core activities and mission of the Centre
  • Ability to handle more than one project at a time
  • Communicate effectively across all CPDC departments
  • Troubleshoot problems
  • Work under minimal supervision
  • Mentor and direct junior process chemists
  • Ability to work day and/or evening shifts

Required Education/Experience/Knowledge:

  • BSc/MSc in a science or engineering field with 10 years of industrial experience in pharmaceutical industry (5 years with PhD), including 2 years of experience in development, formulation, or tech transfer of manufacturing processes;
  • Strong chemistry, process chemistry or aseptic manufacturing experience in a pharmaceutical setting is considered an asset;
  • Outstanding planning, communication, and collaboration skills;
  • Functional knowledge of validation principles, standard concepts, practices, procedures and requirements of GMPs and applicable Health Canada, FDA, EMA, ICH and PDA guidelines;
  • Demonstrated ability to see beyond own function to understand business issues and implement best practices;

If you require accommodation for your application or interview, please contact Human Resources directly at 905.525.9140 ext. 21112 or by email at careers@imagingprobes.ca

We thank all those who apply but only candidates selected for interviews will be contacted.

contact

CanProbe is located in Toronto’s Discovery District with facilities in the University Health Network’s Toronto General Hospital.

If you are interested in working with CanProbe to take your radiopharmaceutical study to the next level, contact us at info@canprobe.ca

Partners

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